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Why does rifampin need to be taken on an empty stomach? You should take rifampicin 'on an empty stomach '. This means that you should take your doses about an hour before a meal, or wait until two hours afterwards. This is because your body absorbs less rifampicin if taken at the same time as food, which means it is less effective.
Can rifampin be used alone? Resistance to rifampin develops rapidly when it is used alone ; it never should be used as monotherapy for any serious infection. Rifampin is the drug of choice for chemoprophylaxis against both organisms. The use of rifampin in treating staphylococcal endocarditis and chronic osteomyelitis remains controversial.
Does Rifampin cause nausea? Side Effects. This drug may cause upset stomach, heartburn, nausea, menstrual changes, headache, drowsiness, or dizziness. If any of these effects persist or worsen, inform your doctor promptly. Rifampin may rarely cause serious liver disease.
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